Oprahs Weight Loss 2025. Oprah’s weight loss journey took a pivotal turn when she began to focus not just on losing weight but on embracing a healthier mindset. Shame, blame and the weight loss revolution airs at 8 p.m.

To begin living her best life, oprah’s speaking candidly about what she calls the brown elephant in the room—her weight gain. For one year, these eight determined women—and oprah!—ate better, moved more, stressed less and made their health priority number one.